1. Wu MR*, Nissim L*, Stupp D*, Pery E, Binder-Nissim A, Weisinger K, Enghuus C, Palacios SR, Humphrey M, Zhang Z, Novoa EM, Kellis M, Weiss R, Rabkin SD, Tabach Y, and Lu TK. A High-Throughput Screening and Computation Platform for Identifying Synthetic Promoters with Enhanced Cell-State Specificity (SPECS). Nature Communications 10(1): 2880, 2019. * denotes equal contributions.

  2. Wu MR, Jusiak B, and Lu TK. Engineering advanced cancer therapies with synthetic biology. Nature Reviews Cancer 19(4): 187-195, 2019. 

  3. Gacerez AT, Wu MR, Cook WJ, and Sentman CL. DAP10 costimulatory signaling promotes potent anti-tumor activity in CAR T cells (Submitted).

  4. Cao J, Perez-Pinera, Lowenhaupt Ky, Wu MR, Purcell O, Fuente-Nunez C, and Lu TK. Versatile and on-demand biologics co-production in yeast. Nature Communications 9(1):77, 2018.

  5. Lee G, Atia L, Lan B, Sharma Y, Nissim L, Wu MR, Pery E, Lu TK, Park CY, Butler JP, and Fredberg JJ. Contact guidance and collective migration in the advancing epithelial monolayer. Connective Tissue Research 59(4):309-315, 2018.

  6. Wu MR*, Nissim L*, and Lu TK. Principles of Systems Biology, No. 23. Synthetic Gene Circuit for Cancer Immunotherapy: Turing Cancer Cells against Themselves. Cell Systems 5, 428-430, 2017. * denotes equal contributions.

  7. Nissim L*, Wu MR*, Pery E, Binder-Nissim A, Suzuki HI, Stupp D, Wehrspaun C, Tabach Y, Sharp PA, and Lu TK. Synthetic RNA-based immunomodulatory gene circuits for cancer immunotherapy. Cell 171(5):1138-1150.e15, 2017. * denotes equal contributions.​

  8. Sentman ML, Murad JM, Cook WJ, Wu MR, Reder J, Baumeister SH, Dranoff G, Fanger MW, and Sentman CL. Mechanisms of acute toxicity in NKG2D chimeric antigen receptor T cell-treated mice. Journal of Immunology 197: 4674-4685, 2016.

  9. Wu MR, Zhang T, Gacerez AT, Coupet TA, DeMars LR, and Sentman CL. B7H6-specific bispecific T cell engagers lead to tumor elimination and host anti-tumor immunity. Journal of Immunology 194(11): 5305-11, 2015.

  10. Wu MR, Zhang T, Alcon A, and Sentman CL. DNAM-1 based chimeric antigen receptors enhance T cell effector function and exhibit in vivo efficacy against melanoma. Cancer Immunology, Immunotherapy 64(4): 409-18, 2015.

  11. Wu MR, Zhang T, DeMars LR, and Sentman CL. B7H6-specific chimeric antigen receptors lead to tumor elimination and host immunity. Gene Therapy 22(8): 675-84, 2015.

  12. Johnson ME, Mahoney JM, Taroni J, Sargent JL, Marmarelis E, Wu MR, Varga J, Hinchcliff ME, and Whitfield ML. Experimentally-derived fibroblast gene signatures identify molecular pathways associated with distinct subsets of systemic sclerosis patients in three independent cohorts. PLoS One 10: e0114017, 2015.

  13. Wu MR, Cook WJ, Zhang T, and Sentman CL. Targeting multiple types of tumors using   NKG2D-coated iron oxide nanoparticles. Nanotechnology 25: 475101, 2014.

  14. Spear P, Wu MR, Sentman ML, and Sentman CL. NKG2D ligands as therapeutic targets. Cancer Immunity 13: 8, 2013.

  15. Zhang T, Wu MR, and Sentman CL. An NKp30-based chimeric antigen receptor promotes T cell effector functions and antitumor efficacy in vivo. Journal of Immunology 189: 2290-2299, 2012.

  16. Lee H, Yuan C, Hammet A, Mahajan A, Chen ES, Wu MR, Su MI, Heierhorst J, and Tsai MD. Diphosphothreonine-specific interaction between an SQ/TQ cluster and an FHA domain in the Rad53-Dun1 kinase cascade. Molecular Cell 30: 767-778, 2008.

© 2019 by Lab for Synthetic Immunity